Report on Carcinogenesis Bioassay of Chlordane and Heptachlor

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Chlordane and Heptachlor

Chlordane and heptachlor were considered together because of their close structural similarity and because technical-grade products each contain about 10–20% of the other compound. These substances were considered by previous working groups, in 1978 (IARC, 1979), 1987 (IARC, 1987) and 1990 (IARC, 1991). Since that time, new data have become available, and these have been incorporated into the m...

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Bioassay of heptachlor for possible carcinogenicity.

A bioassay of technical-grade heptachlor for possible carcinogenicity was conducted by administering the test material in feed to Osborne-Mendel rats and B6C3F1 mice. Groups of 50 rats of each sex were administered low or high concentrations of the heptachlor for 80 weeks, then observed for 30 weeks. Doses for females were first increased, but because of toxic effects the doses were then reduce...

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Bioassay of chlordane for possible carcinogenicity.

A bioassay of analytical-grade chlordane for possible carcinogenicity was conducted by administering the test material in feed to Osborne-Mendel rats and B6C3F1 mice. Groups of 50 rats of each sex were administered low or high concentrations of the chlordane for 80 weeks, then observed for 29 weeks. Because of toxic effects, doses were reduced for both male and female rats during the course of ...

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Heptachlor and Heptachlor Epoxide

9. REFERENCES ACGIH. 1986. Documentation of the threshold limit valves and biological exposure indices. 5th ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, 296. ACGIH. 2004. Threshold limit values for chemical substances and physical agents and biological exposure indices. Cincinnati, OH: American Conference of Governmental Industrial Hygienists. Adeshina F, Todd ...

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PERSISTENT ORGANIC POLLUTANTS An Assessment Report on: DDT-Aldrin-Dieldrin-Endrin-Chlordane Heptachlor-Hexachlorobenzene Mirex-Toxaphene Polychlorinated Biphenyls Dioxins and Furans

The main objective of the IPCS is to carry out and disseminate evaluations of the effects of chemicals on human health and the quality of the environment. Supporting activities include the development of epidemiological, experimental laboratory, and risk-assessment methods that could produce internationally comparable results, and the development of human resources in the field of chemical safe...

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ژورنال

عنوان ژورنال: The Bulletin of the Society of Pharmacological and Environmental Pathologists

سال: 1977

ISSN: 0094-1824

DOI: 10.1177/019262337700500408